The 1,3-beta-D-Glucan (BDG) assay is widely used for the diagnosis of fungal infections, especially in patients with hematologic malignancies. Some antimicrobials have been reported to cause false-positive results for BDG, but there has been no report on the effect of penicillin G (PCG) on BDG level.
Conclusions: IVIG administration leads to false positive BDG levels in the vast majority of patients. Elevated BDG levels may be detectable for more than two weeks after IVIG administration, while BDG levels normalized within 3 weeks in all patients. Therefore, BDG should not be used to diagnose IFD within three weeks after IVIG administration.
2/1/2018 · Immunoglobulin preparations (IVIG) contain high amounts of (1–3)-ß-D-Glucan (BDG). • IVIG administration leads to false positive BDG serum levels in most patients. • After IVIG administration BDG levels may remain elevated for more than 2 weeks. • 3 weeks after IVIG administration, BDG serum levels normalize in all patients.
7/1/2014 · This study was undertaken to examine the performance of the Fungitell ?- glucan (BG) assay, to compare it with that of the galactomannan (GM) test for the diagnosis of invasive aspergillosis (IA) in patients with hematological malignancies, and to examine the rates of false -positive BG and GM test results due to ?-lactam antibiotics among sera of patients with Gram-positive or Gram-negative …
Introduction: Serum (1-3)- beta – d – glucan (BDG) assay has been proposed as an adjunct for the rapid diagnosis of invasive fungal infection (IFI).However, false -positive results have been reported following transfusion of blood products in adults. Aims: To assess the relationship between blood product transfusion and elevated BDG in neonates.. Method: Retrospective study including neonates ?32 …
Beta-d-Glucan Detection as a Diagnostic Test for Invasive …
(1–3)-?-D-Glucan Assay: A Review of its Laboratory and …
(1–3)-?-D-Glucan Assay: A Review of its Laboratory and …
Use and Limits of (1-3)-?-d-Glucan Assay (Fungitell …
